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S.ravi
Advanced Member


India
4205 Posts

Posted - 07/06/2009 :  11:06:50  Show Profile Send S.ravi a Private Message  Reply with Quote
Five cups of coffee daily 'can keep Alzheimer's at bay'
Washington (PTI): Coffee buffs may have another reason to pour that extra cup, for researchers have found that drinking five cups of the hot beverage everyday can help stave off Alzheimer's disease.

A new study by South Florida University has revealed that downing caffeine equivalent of five cups of coffee a day can reverse memory impairment, the latest edition of 'Journal of Alzheimer's Disease' reported.

According to the researchers, caffeine significantly decreases abnormal levels of the protein linked to Alzheimer's disease, both in the brains and in the blood.

"The new findings provide evidence that caffeine could be a viable treatment for established Alzheimer's disease, and not simply a protective strategy. That's important as caffeine easily enters the brain, and it appears to directly affect the disease process," lead researcher Gary Arendash said.

In fact, the researchers have based their findings on an analysis of aged laboratory rodents who're bred to develop symptoms of Alzheimer's disease in old age -- the study found that caffeine in early adulthood prevented the onset of memory problems in those mice who had caffeine.

S.ravi
Advanced Member



India
4205 Posts

Posted - 07/06/2009 :  11:08:49  Show Profile Send S.ravi a Private Message  Reply with Quote
Caffeine reverses memory loss?
Washington (IANS): Caffeine given daily to ageing mice with Alzheimer's reversed their memory loss, says a new study.

The new findings provide evidence that caffeine could be a viable 'treatment' for established Alzheimer's disease, and not simply a protective strategy," said study author Gary Arendash, University of South Florida (USF).

"That's important because caffeine is a safe drug for most people, it easily enters the brain, and it appears to directly affect the disease process," he added.

Buoyed by these findings, Florida researchers hope to begin human trials to evaluate their effectiveness in people with mild cognitive impairment or early Alzheimer's disease, said Huntington Potter, investigator for the caffeine studies.

The research group has already determined that caffeine administered to elderly non-demented humans quickly affects their blood levels of Beta-amyloid, just as it did in the Alzheimer's mice.

"These are some of the most promising Alzheimer's mouse experiments ever done showing that caffeine rapidly reduces Beta-amyloid protein in the blood, an effect that is mirrored in the brain, and this reduction is linked to cognitive benefit," Potter said.

"Our goal is to obtain the funding needed to translate the therapeutic discoveries in mice into well-designed clinical trials," he added, according to an USF release.

Arendash and colleagues became interested in caffeine's potential for treating

Alzheimer's, after a Portuguese study reported that people with Alzheimer's had consumed less caffeine over the last 20 years than people without the

neuro-degenerative disease.

These findings were published online in the Journal of Alzheimer's Disease.


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